Identification of Salmonella typhi by PCR among recipients of oral typhoid vaccine lots
نویسندگان
چکیده
منابع مشابه
Early diagnosis of typhoid fever by nested PCR for flagellin gene of Salmonella enterica serotype Typhi
BACKGROUND & OBJECTIVES Typhoid fever caused by Salmonella Typhi continues to be a major health problem in spite of the use of antibiotics and the development of newer antibacterial drugs. Inability to make an early laboratory diagnosis and resort to empirical therapy, often lead to increased morbidity and mortality in cases of typhoid fever. This study was aimed to optimize a nested PCR for ea...
متن کاملIntroduction of Shigella flexneri 2a type and group antigen genes into oral typhoid vaccine strain Salmonella typhi Ty21a.
For protection against dysentery caused by Shigella flexneri 2a, an in vivo-constructed recombinant plasmid with genes specifying the S. flexneri type and group antigens located near the pro (min 6) and his (min 44) chromosomal markers, respectively, was made and transferred to the galE Salmonella typhi strain Ty21a. Strain Ty21a carrying this recombinant plasmid was shown by immunological and ...
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Unlike many of the nontyphoidal Salmonella serovars such as S. Typhimurium that cause restricted gastroenteritis, Salmonella Typhi is unique in that it causes life-threatening typhoid fever in humans. Despite the vast difference in disease outcomes that S. Typhi and S. Typhimurium cause in humans, there are few genomic regions that are unique to S. Typhi. Of these regions, the most notable is t...
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The Department publishes M&I, its newsletter, once a year. Highlighting exciting new research discoveries, exceptional faculty achievements, and department-wide initiatives , M&I provides a comprehensive summary of the goings-on in the department. A digital version is also available at: 03 MESSAGE Message from the Chair 07 RESEARCH A Model for Personalized in vivo Analysis of Human Immune Respo...
متن کاملEarly Diagnosis of Typhoid By PCR For FliC-d Gene of Salmonella Typhi in Patients Taking Antibiotics.
OBJECTIVE To compare PCR (Polymerase Chain Reaction) with blood culture, typhi-dot and Widal test for the diagnosis of typhoid in patients taking antibiotics. STUDY DESIGN Cross-sectional, comparative study. PLACE AND DURATION OF STUDY National University of Sciences and Technology, Islamabad, Pakistan, from April 2013 to August 2014. METHODOLOGY One hundred and five patients were include...
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ژورنال
عنوان ژورنال: Journal of Clinical Microbiology
سال: 1994
ISSN: 0095-1137,1098-660X
DOI: 10.1128/jcm.32.4.1133-.1994